In the black and white images, which were shot by photography duo Mert Alas and Marcus Piggott, the actress' iconic smile is replaced with an intense, hard-looking gaze.
Givenchy creative director Riccardo Tisci told WWD: 'The mood of the show was about this very powerful woman, and Julia represents this very much. She represents the couture part. It's important to show your iconic work. I want to build what is the real classic wardrobe.'
Tisci has been dressing Julia Roberts for red carpet appearances since 2013, and the actress wore a couture Givenchy gown to the 2014 Oscars.
Wiping away the Pretty Woman image, Julia Roberts is captured with minimal hair and make-up. 'I decided to make her more intellectual, more serious, more pure,' Tisci told WWD. 'It's a different, fresh, new way to see Julia – really cool and urban, I think… I think it's a very honest campaign.'