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Daenerys' Essos love interest was played by Ed Skrein in season and Michiel Huismanfrom season 4 onward.
The older Clegane brother has been recast multiple times. Conan Stevens portrayed the character in season 1, Ian Whyte played him in season 2, and Hafþór Júlíus Björnsson took over the role beginning in season 4.
Callum Wharry played Cersei's youngest son in seasons 1 and 2, and Dean-Charles Chapman took over the role in season 4, when the part became bigger.