Alto Atacama, San Pedro de Atacama

A true five-star hideaway, Alto Atacama is made up of a circle of rustic chic adobe buildings. It’s the setting that really wows, though. There’s biking, hiking and 4WD trips to geysers at sunrise, flamingo-spotting on the salt lakes, driving across the salt planes, or visiting the 12th-century ruins of Pukara de Quitor or the eerie Moon Valley. If that all sounds exhausting, you can finish a day off with a spot of star-gazing from the Jacuzzi or while sipping a pisco sour by the fire pit.

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Hangaroa Eco Village, Easter Island

Separated from its nearest neighbour by over 1,200 miles of Pacific Ocean, Easter Island is the world’s most remote habited island. So it almost goes without saying that even if you leave aside the iconic moai statues and a stay at the newly opened, and very stylish, Hangaroa Eco Village, a trip there is likely to be pretty special…

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Elqui Domos, Elqui Valley

Another one for stargazers and wilderness-lovers, Elqui Domos is in the heart of the stunning Elqui Valley. Setting aside, divided between geodesic domes – a series of luxury tents, essentially – and stilted houses, the ‘rooms’ are also very special indeed.

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The Singular, Patagonia

There are plenty more vast empty spaces on offer in Chilean Patagonia at The Singular. A renovated Victorian era cold-storage plant on the shores of Last Hope Sound, it’s a place where stripped back industrial-style design meets the bare landscape of snowy mountains rolling down to the ocean to absolutely stunning effect.

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The Aubrey, Santiago

In a list of special places to stay, at first glance The Aubrey stands out for being a bit, well, normal. On closer inspection, though, it more than matches the other places we’ve picked out. Why? The interiors. Santiago’s original boutique hotel came about as a result of three years (and several million dollars) of renovation work on a beautiful 20s mansion in bohemian Bellavista. Inside, there are parquet floors, Tom Dixon lamps, sofas clad in leather and velvet, and stunning Art Deco notes throughout. Special doesn’t begin to describe it.

Read our full review of The Aubrey

Like our pick of special places to stay in Chile, and looking for something else suitably off-the-beaten track? Check out our pick of the best African safari lodges. Or see our entire collection of places to stay.